Memory biomarkers confirm aerobic exercise helps cognitive function in older adults ANI | Updated: Jun 14, 2021 09:31 IST
Washington [US], June 14 (ANI): Until now, systemic biomarkers to measure exercise effects on brain function and that link to relevant metabolic responses were lacking. A recent study shows a memory biomarker, myokine Cathepsin B (CTSB), increased in older adults following a 26-week structured aerobic exercise training.
The positive association between CTSB and cognition, and the substantial modulation of lipid metabolites implicated in dementia, support the beneficial effects of exercise training on brain function and brain health in asymptomatic individuals at risk for Alzheimer s.
Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer s disease (AD). In ageing humans, aerobic exercise training increases grey and white matter volume enhances blood flow and impr
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IMAGE: The enhanced physical activity group underwent 26 weeks of supervised treadmill training. Blood samples for both groups were taken at baseline and after 26 weeks. view more
Credit: Florida Atlantic University
Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer s disease (AD). In aging humans, aerobic exercise training increases gray and white matter volume, enhances blood flow, and improves memory function. The ability to measure the effects of exercise on systemic biomarkers associated with risk for AD and relating them to key metabolomic alterations may further prevention, monitoring, and treatment efforts. However, systemic biomarkers that can measure exercise effects on brain function and that link to relevant metabolic responses are lacking.