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Scientific American Preventing the Next Pandemic An influenza pandemic like that of 1918 could make the scourge of COVID-19 look mild. A vaccine to prevent it may finally be possible. This article was produced for Sabin Vaccine Institute by Scientific American Custom Media, a division separate from the magazine s board of editors. Prototype universal influenza vaccines such as this one, a nanoparticle with a protein scaffold (blue) studded with influenza hemagglutinin proteins (green), could provoke an immune response to all human influenza subtypes. Credit: NIAID  Between 1918 and 1920, the ‘Spanish flu’ infected a third of the world’s population, and caused an astronomical 17 million deaths. A century later, we have yet to develop defenses against an equally devastating influenza pandemic, says Stacey Knobler, senior director at the Sabin Vaccine Institute.

Camp funstonUnited statesNeil kingStacey knoblerTed rossDavid bakerSarah cobeyPatrick wilsonNational institute of allergySabin vaccine instituteRagon institute of massachusettsUniversity of georgiaSabin vaccine institute influenzer initiativeCollaborative influenza vaccine innovation center civicsNational museum of healthUniversity of washington