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Covid vacccine: Common bowel disease treatment may blunt COVID-19 vaccine response: Study


Synopsis
This is a really important study, showing that a single dose of SARS-CoV2 vaccine is insufficient to generate protective antibody responses in patients treated with anti-TNF drugs, said Nick Powell, co-senior author of the study from Imperial s Department of Metabolism, Digestion and Reproduction.
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People who take a commonly-prescribed medicine for inflammatory bowel disease (IBD) should not assume they are protected after a first dose of COVID-19 vaccine, according to a study that found many such people had poor antibody response. The study, published in the journal GUT, measured antibody response after vaccination with the Pfizer/BioNTech or the Oxford/AstraZeneca COVID-19 vaccine in 865 people treated with infliximab, an anti-tumour necrosis factor (anti-TNF) drug, prescribed to around two million people worldwide. ....

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