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Oncopeptides announces three abstracts accepted by the 2021 American Society of Clinical Oncology


Oncopeptides announces three abstracts accepted by the 2021 American Society of Clinical Oncology
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WALTHAM, Massachusetts, May 19, 2021 /PRNewswire/
Oncopeptides AB (publ) (Nasdaq Stockholm: ONCO), a global biotech company focused on the development of therapies for difficult-to-treat hematological diseases, today announces that three abstracts with data on PEPAXTO
® (melphalan flufenamide, also known as melflufen) in relapsed refractory multiple myeloma, have been accepted by the 2021 American Society of Clinical Oncology, ASCO, and have now been published online. The clinical data presentations include updates on Oncopeptides ANCHOR and LIGHTHOUSE studies as well as a pooled analysis of the O-12-M1 and HORIZON studies in patients who have been exposed to or become refractory to prior alkylators. ....

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iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its ...


Press release content from Globe Newswire. The AP news staff was not involved in its creation.
iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its .
iTeos Therapeutics Inc.April 10, 2021 GMT
Initial data from the Phase 1 dose escalation part of the Phase 1/2a trial in adult patients with advanced solid tumors indicated EOS-448 was generally well tolerated with no dose-limiting toxicities observed
EOS-448 showed preliminary signs of clinical activity as a monotherapy, including a partial response in one pembrolizumab-resistant melanoma patient, and stable disease in multiple patients
EOS-448 reduced TIGIT
+
suppressive T regulatory cells and CD8 T cells considered to be exhausted at all tested doses, indicating engagement of FcγR, an essential component in many immune system effector functions ....

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