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Frontiers | An Update on Protective Effectiveness of Immune Responses After Recovery From COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits variable immunity responses among hosts based on symptom severity. Whether immunity in recovered individuals is effective for avoiding reinfection is poorly understood. Determination of immune memory status against SARS-CoV-2 helps identify reinfection risk and vaccine efficacy. Hence, after recovery from COVID-19, evaluation of protective effectiveness and durable immunity of prior disease could be significant. Recent reports described the dynamics of SARS-CoV-2 -specific humoral and cellular responses for more than six months in convalescent SARS-CoV-2 individuals. Given the current evidence, NK cell subpopulations, especially the memory-like NK cell subset, indicate a significant role in determining COVID-19 severity. Still, the information on the long-term NK cell immunity conferred by SARS-CoV-2 infection is scant. The evidence from vaccine clinical trials and observational studies indicates that hybrid natural/ ....

Eastern Cape , South Africa , Western Cape , Saudi Arabia , United Kingdom , South Korea , Free State , Yunbao Pan , Paige Lawrence , Zhengm Tim , Cohen Tervaert , Cullym Exosome , Jernbom Falk , Nasrin Shokrpour , Shiraz University Of Medical Science , Health Sci , Terminal Differentiation Of Plasma Cells In Health , Shiraz University Of Medical Sciences , Development Of Clinical Research Nemazee Hospital , S Specific Igg , Natural Immunity , Vaccine Immunity , Shiraz University , Medical Science , Medical Sciences , Clinical Research ,

Frontiers | Healthcare Workers in South Korea Maintain a SARS-CoV-2 Antibody Response Six Months After Receiving a Second Dose of the BNT162b2 mRNA Vaccine

Background: Effective vaccines against coronavirus disease 2019 (COVID-19) are available worldwide; however, the longevity of vaccine effectiveness is not known. Objective: We performed a prospective observational study to assess the antibody response of healthcare workers against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after BNT162b2 mRNA COVID-19 vaccination. Methods: SARS-CoV-2 neutralizing antibody (nAb) and spike (S) protein-IgG (S-IgG) antibody titers were examined in participants who received two doses of the BNT162b2 mRNA COVID-19 vaccine in a single center between March 1, 2021, and October 11, 2021. Antibody levels were analyzed at four times: before vaccination (visit 1), 4 weeks after the first vaccination (visit 2), 3 months after the second vaccination (visit 3), and 6 months after the second vaccination (visit 4). Results: A total of 249 healthcare workers at Jeju National University Hospital were enrolled in this study, and 982 blood samples were an ....

Ha Afon , Jeju Island , Cheju Do , South Korea , United States , South Africa , Republic Of Korea , Moreira Ed Jr , Johnson Janssen , Abbot Korea Ltd , Jeju National University Hospital , Large Integrated Health System , Prevention Agency , Department Of Laboratory Medicine , Vaccine Among Us Health Care Personnel , Departments Of Laboratory Medicine , Abbott Ireland Diagnostics Division , Institutional Review Board , Laboratory Medicine , Korean Peninsula , Fully Vaccinated , Supplementary Figure , Korea Disease Control , Abbot Korea , Supplementary Material , Retrospective Cohort ,

New perspective on SARS-CoV-2 breakthrough infections and booster shot restoration of vaccine efficacy

A recent article published in the journal Science explains how SARS-CoV-2 variants can bypass vaccine-induced immune defenses. However, immunity is restorable with a booster shot. The paper's authors outlined the importance of a booster shot in maintaining immunity and preventing severe infection. ....

United States , Oxford Astrazeneca , Centers For Disease , World Health Organization , Image Credit , Immunity After , Long Covid , Disease Control , Coronavirus Disease Covid 19 , Ars Cov 2 , Covid 19 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

Naučnici u Austriji istraživali su koliko traje IMUNITET NAKON PRELEŽANE KORONE i došli su do baš velike brojke

Naučnici u Austriji istraživali su koliko traje IMUNITET NAKON PRELEŽANE KORONE i došli su do baš velike brojke
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