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<p>Tuberculosis, caused by the bacterium <em>Mycobacterium tuberculosis</em> (Mtb) kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide&mdash;and that number is only growing larger. How, exactly, Mtb evades the immune system isn&rsquo;t yet known, but a collaborative team of researchers from the University of Massachusetts Amherst and Seattle Children&rsquo;s Research Institute recently discovered something surprising: prior exposure to a genus of bacteria called <em>Mycobacterium</em> seems to remodel the first-line defenders in the body&rsquo;s immune system. Furthermore, how those cells are remodeled depends on exactly how the body is exposed. These results, published recently in <a href="https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011871"><em>PLOS Pathogens</em></a><em>,</em> suggest that a more

Daegan millerKevin urdahlAlissa rothchildSeattle children research instituteandAnimal sciences departmentNational institute of allergyNational institutes of healthSeattle children research instituteUniversity of massachusetts amherstMassachusetts amherstSeattle childrenResearch instituteTrojan horseDat maiResearch instituteandNational institutes