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Astellas' Fezolinetant Reduces Frequency and Severity of VMS Associated with Menopause in Women Considered Unsuitable for Hormone Therapy

Phase 3b DAYLIGHT study being presented at ESG 2023 demonstrated fezolinetant 45 mg achieved statistically significant reductions in the frequency and severity of moderate to severe vasomotor symptoms due to menopause and patient-reported sleep disturbance at 24 weeks Women considered unsuitable included those with contraindications, who are averse to taking, have stopped taking or have conditions that suggest caution in using hormone therapy Results will support health technology a. ....

Noord Holland , Rossella Nappi , Naoki Okamura , San Matteo Foundation , University Of Pavia , European Society Of Gynecology , Astellas Pharma Inc , Head Of Biopharma Development , Research Center , Health Qual Life Outcomes , Astella Fezolinetant Reduces Frequency , Women Considered Unsuitable , European Society , Full Professor , Reproductive Medicine , Gynecological Endocrinology , Menopause Unit , Imatteo Foundation , Vice President , Biopharma Development , Short Form , Focus Area Approach , Equal Life , Clin Endocrinol , Press Release Image , Patient Reported ,

Rossella Nappi: taking the stigma out of menopause

A few years ago, Rossella Nappi was scheduled to speak at a conference for obstetricians
and gynaecologists. “A lot of people were waiting and I was in a rush, as usual”,
recalled Nappi, who is professor of obstetrics and gynaecology at the University of
Pavia (Pavia, Lombardy, Italy) and chief of reproductive medicine at the IRCCS San
Matteo Foundation in the same city. The day of the conference was hot and Nappi had
come from outside. Inside, everything was air-conditioned. She got onto the podium
and said “could you please wait a second? I have to drink a glass of water I am having
a hot flush.” Nappi felt a shift in the mood of the room; her words had unsettled
the audience. ....

Rossella Nappi , San Matteo Foundation , University Of Pavia , Imatteo Foundation , Lancet Diabetes ,