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Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

A secondary analysis from the SWOG S0931 EVEREST trial has found that in the subgroup of patients with clear-cell renal cell carcinoma (RCC) who were at very-high risk of recurrence, those who were treated with everolimus after surgery had a statistically significant improvement in recurrence-free survival compared to patients getting placebo after surgery. ....

Oregon , United-states , Spain , San-antonio , Texas , Madrid , Maxwell-meng , Igor-puzanov , Primon-lara-jr , Ajjais-alva , Josephi-clark , Neeraj-agarwal

High-Risk Renal Cell Carcinoma Patients Benefit from Everolimus

High-Risk Renal Cell Carcinoma Patients Benefit from Everolimus
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San-antonio , Texas , United-states , Spain , Madrid , Oregon , Naomib-haas , Tonik-choueiri , Markn-stein , Ianm-thompson , Ulkan-vaishampayan , Sumantak-pal

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

A new research paper was published in Oncotarget's Volume 14 on June 19, 2023, entitled, "Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer." ....

Megan-craig , Brian-hernandez , Ianm-thompson , Devalingam-mahalingam , John-kuhn , Salih-hanni , Paromitta-datta , Sureshkumar-mulampurath-achutan-pillai , Anthonyv-serritella , Joel-michalek , Ofelia-romero , Michael-pollak