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Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

In patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran reduced triglyceride levels by an average of 74% after 24 weeks of use without causing any significant safety concerns, according to research presented at the American College of Cardiology's Annual Scientific Session.

Montreal
Quebec
Canada
Daniel-gaudet
Arrowhead-pharmaceuticals
University-of-montreal
American-college-of-cardiology-annual-scientific-session
American-college-of-cardiology
American-college
Annual-scientific
Triglyceride
Acute-pancreatitis

High dietary insulin index associated with increased risk of metabolic unhealthiness, research show

Study explored the association between dietary insulin index (DII) and dietary insulin load (DIL) with metabolic healthy (MH) status and the serum levels of brain-derived neurotrophic factor (BDNF) and adropin among the Iranian adult population.

Iran
Isfahan
Esfahan
Iranian
Scientific-reportsstudy
Insulin
Research
Flood
Blood-pressure
Rain
Hronic

Higher Triglycerides Linked to Lower Dementia Risk

Older patients with higher triglyceride levels, mostly within the normal to high range, had lower risk of dementia and slower cognitive decline over time than those with lower triglyceride levels.

United-kingdom
Australia
Melbourne
Victoria
Monash
South-australia
Australian
Zhen-zhou
Research-foundation
School-of-public-health
Monash-university
Royal-australian-college

Pegozafermin associated with improved outcomes in nonalcoholic steatohepatitis

1. In this randomized controlled trial, treatment with pegozafermin improved fibrosis in patients with nonalcoholic steatohepatitis (NASH). 2. Treatment with pegozafermin led to increased rates of NASH resolution. Evidence Rating Level: 1 (Excellent) Study Rundown: NASH is a disease characterized by hepatic inflammation and excess fat accumulation with or without fibrosis of the liver. Pegozafermin

Minute-medicine-inc
Rating-level
Controlled-trial
Confidence-interval
Chronic-disease
Fibrosis
Gastroenterology
Hepatology
Hypertriglyceridemia
Nash
Nonalcoholic-steatohepatitis-outcomes

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