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Democratizing DNA-based health risk scores
Hutch-led consortium receives $9.8M grant to improve genetic risk prediction for cardiovascular disease in racially and ethnically diverse populations
December 10, 2020
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By Diane Mapes
/ Fred Hutch News Service
Photo illustration by Getty Images
For more than a decade, scientists with the PAGE consortium (Population Architecture using Genomics and Epidemiology) have been focused on developing polygenic risk scores  those statistical estimates of a person’s risk for disease based on their genes  that will accurately predict risk in all major racial and ethnic groups in the U.S.
This is crucial since the Human Genome Project and a lot of the of genetic research done since  has focused almost exclusively on people of European ancestry. As a result, polygenic risk scores designed to help clinicians and the general population gauge their susceptibility to ....

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