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Dietary sugars and gut microbes play a key role in promoting malaria parasite infection in mosquitoes. Researchers in China have uncovered evidence that mosquitoes fed a sugar diet show an increased abundance of the bacterial species Asaia bogorensis, which enhances parasite infection by raising the gut pH level. The study appears April 20 in the journal
Cell Reports. Our work opens a new path for investigations into the role of mosquito-microbiota metabolic interactions concerning their disease-transmitting potential, says co-senior study author Jingwen Wang of Fudan University in Shanghai, China. The results may also provide useful insights for the development of preventive strategies for vector control.
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Heidelberg/Germany, 14 December 2020 - Molecular markers in the blood shown to be predictive of severe COVID-19 outcomes resulting from SARS-CoV-2 coronavirus infection have been identified in a study by a Chinese research team. The study results extend understanding of the pathophysiology and clinical progress of COVID-19 with potential for identifying early during the course of infection which individuals are most at risk of developing severe conditions and requiring hospital care.
In addition to pneumonia and septic syndrome, a smaller proportion of patients have also developed severe gastrointestinal and/or cardiovascular symptoms as well as neurological manifestations after SARS-COV-2 infection. This is possible because the angiotensin-converting enzyme 2 (ACE 2) receptor used by SARS-COV-2 for cell entry is found in other organs beside the lungs, including the heart, liver, kidney, pancreas, small intestines and also the CNS (Central Nervous System), especially the g