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Hijacked immune activator promotes growth and spread of colorectal cancer

Hijacked immune activator promotes growth and spread of colorectal cancer
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Baden Wüberg , Jun Zhou , Erica Valentini , Michael Boutros , German Consortium For Translational Cancer Research , National Center , German Cancer Research Center Deutsches Krebsforschungszentrum , Helmholtz Association Of German Research Centers , Cancer Information Service , German Cancer Research Center , Hopp Children Tumour Center Ki , University Of Heidelberg , German Centers For Health Research , Ministry Of Education , Developmental Cell , Deutsches Krebsforschungszentrum , Information Service , Tumor Diseases , Hopp Children , Tumour Center , German Consortium , Translational Cancer Research , German Centers , Health Research , Federal Ministry , Helmholtz Association ,

High-throughput metabolic profiling of single cells

High-throughput metabolic profiling of single cells
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Baden Wüberg , Prasad Phapale , Mathias Heikenwalder , Mathias Heikenw , Theodore Alexandrov , Sergio Triana , Luca Rappez , Mira Stadler , Rosem Gathungu , Katja Ovchinnikova , German Consortium For Translational Cancer Research , National Center , German Cancer Research Center Deutsches Krebsforschungszentrum , Helmholtz Association Of German Research Centers , Cancer Information Service , European Molecular Biology Laboratory , German Cancer Research Center , Hopp Children Tumour Center Ki , German Centers For Health Research , Ministry Of Education , Matrix Assisted Laser , Non Alcoholic Fatty Liver Disease , Non Alcoholic Steatohepatitis , Deutsches Krebsforschungszentrum , Information Service , Tumor Diseases ,

Blood stem cells make brain tumors more aggressive

Blood stem cells make brain tumors more aggressive
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Baden Wüberg , West German , Anita Steinbach , Celia Dobersalske , Shruthi Prasad , Vivien Ullrich , Martin Glas , Igor Cima , Sarah Teuber Hanselmann , Jenst Siveke , Tobias Blau , German Consortium For Translational Cancer Research , National Center , Nature Communications , German Cancer Consortium , German Cancer Research Center Deutsches Krebsforschungszentrum , German Tumor Center , Cancer Information Service , Helmholtz Association Of German Research Centers , Department Of Neurosurgery At Essen University Hospital , Heidelberg University Hospital , German Cancer Research Center , Hopp Children Tumour Center Ki , German Centers For Health Research , Ministry Of Education , Translational Oncology ,

How "paralyzed" immune cells can be reactivated against brain tumors

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body s immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor. These results confirm that therapeutic vaccines or immunotherapies are more effective against brain tumors if active substances are simultaneously used to promote the suppressed immune system. ....

Baden Wüberg , Michael Platten , Ilona Gutcher , Stefan Pusch , Oliver Schnell , Felix Sahm , Markus Hahn , Gernot Poschet , Franciscoj Quintana , Dieterh Heiland , Wolfgang Wick , Camila Fernandez Zapata , Michael Kilian , Marco Prinz , Lukas Bunse , Sabine Heiland , Theresa Bunse , Tobias Kessler , Josef Priller , Mirco Friedrich , Khwab Sanghvi , Edward Green , Miriam Ratliff , Roman Sankowski , Denis Abu Sammour , Daniel Schrimpf ,

Vaccination against mutated protein tested in brain tumor patients for the first time

Vaccination against mutated protein tested in brain tumor patients for the first time
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Baden Wüberg , Michael Platten , Michael Breckwoldt , Antje Wick , Joachimp Steinbach , Geoffreya Behrens , Isabel Poschke , Lisa Marie Rother , Anita Schmitt , Khwab Sanghvi , Oliver Schnell , Felix Sahm , Inga Harting , Edward Green , Neuenheimer Feld , Ghazaleh Tabatabai , Michael Schmitt , Angelika Freitag , Le Cornet , Wolfgang Wick , Martin Bendszus , Dietmar Krex , Sune Justesen , Stefan Stevanovi , Lukas Bunse , Martin Misch ,