A team of scientists from Helmholtz Munich, the LMU University Hospital and the Ludwig-Maximilians Universität München (LMU) have found a way of using of standard antibodies to map whole bodies of mice using fluorescent markers, especially useful for studies of body-wide structures such as the nervous system. Click to read more.
WildDISCO: Visualizing whole bodies in unprecedented detail phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.
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Quick look under skin
Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience. Artificial neural networks open up new possibilities: They require just seconds to interpret whole-body scans of mice and to segment and depict the organs in colors, instead of in various shades of gray. This facilitates the analysis considerably.
How big is the liver? Does it change if medication is taken? Is the kidney inflamed? Is there a tumor in the brain and did metastases already develop? In order to answer such questions, bioscientists and doctors to date had to screen and interpret a wealth of data.
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IMAGE: First author Oliver Schoppe in the Center for Translational Cancer Research at the Technical University of Munich. view more
Credit: Astrid Eckert / TUM
Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience. Artificial neural networks open up new possibilities: They require just seconds to interpret whole-body scans of mice and to segment and depict the organs in colors, instead of in various shades of gray. This facilitates the analysis considerably.
How big is the liver? Does it change if medication is taken? Is the kidney inflamed? Is there a tumor in the brain and did metastases already develop? In order to answer such questions, bioscientists and doctors to date had to screen and interpret a wealth of data.