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FDA Extends Review Time for Investigational Duchenne Agent Givinostat

Givinostat, a histone deacetylase inhibitor from Italfarmaco, was supported by data from the phase 3 EPIDYS study, a randomized, double-blind, placebo-controlled, multicenter trial investigating the agent vs placebo. ....

Paolo Bettica , Italfarmaco Paolo Bettica , Craig Mcdonald , Department Of Pediatrics , Uc Davis Health , Uc Davis Health Craig Mcdonald , Prescription Drug User Fee Act , North Star Ambulatory Assessment , Physical Medicine , Histone Deacetylase ,

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease
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United States , Prasenjit Mondal , Martin Zhang , Brain Health At Massachusetts , Mccance Center , Advanced Science , Massachusetts General Hospital , Mass General Brigham , Brain Health , Massachusetts General , Based Discovery , Small Molecule Inhibitor , Histone Deacetylase , Significantly Reduces Alzheimer , Disease Neuropathology ,