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Sensitive Raman Probe Detects Enzyme Expression in Tissues

Sensitive Raman Probe Detects Enzyme Expression in Tissues
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United States , Yasuyuki Ozeki , Hiroyoshi Fujioka , Tokyo Institute Of Technology Tech , Journal Of The American Chemical Society , University Of Tokyo , Tokyo Tech , Professor Mako Kamiya , Assistant Professor Hiroyoshi Fujioka , Tokyo Institute , American Chemical ,

Highly sensitive Raman probe detects enzyme e

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation. The strategy allows a synthesis of highly activatable Raman probes with high aggregation and multiplexing ability, making it a promising tool for extending the range of Raman probes for the detection of multiple enzyme activities in heterogeneous biological tissues. ....

United States , Yasuyuki Ozeki , Hiroyoshi Fujioka , Journal Of The American Chemical Society , Tokyo Institute Of Technology , University Of Tokyo , Tokyo Institute Of Technology Tech , Method Of Research , Tokyo Tech , Professor Mako Kamiya , Assistant Professor Hiroyoshi Fujioka , Tokyo Institute , American Chemical , Selective Ex Vivo ,