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First-in-Class YAP/TEAD Inhibitor Demonstrates Early Efficacy Targeting Hippo Pathway

Investigators hope that first-in-class agents will combat dysfunction of the Hippo pathway, which promotes YAP and TAZ activation resulting in uncontrolled proliferation and impaired differentiation, by inhibiting the transcription function of TEAD-YAP.

Researchers Report Clinical Proof-of-Concept Data for Vivace Therapeutics VT3989, a First for a Cancer Drug Targeting the Hippo Pathway, in Oral Presentation at AACR 2023

Researchers Report Clinical Proof-of-Concept Data for Vivace Therapeutics VT3989, a First for a Cancer Drug Targeting the Hippo Pathway, in Oral Presentation at AACR 2023

Researchers Report Clinical Proof-of-Concept Data for Vivace Therapeutics VT3989, a First for a Cancer Drug Targeting the Hippo Pathway, in Oral Presentation at AACR 2023
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