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Helen Murray Free, developed with her husband the first dip-and-read diagnostic test for diabetes – obituary

Helen Murray Free with her husband and scientific collaborator Alfred in 1955
Credit: BAYER
Helen Murray Free, who has died aged 98, was the co-developer, with her husband Alfred Free, of Clinistix, the first dip-and-read diagnostic test for diabetes and for monitoring glucose levels in urine, an achievement that revolutionised diagnostic testing.
Before the introduction of Clinistix in 1956, laboratory technicians tested for diabetes by adding a reagent to urine in a test tube and then heating the mixture over a Bunsen burner, a process that was not only cumbersome but also imprecise because it could not distinguish glucose from other sugars.
Working at Miles Laboratories in Indiana, the Frees worked out how to impregnate thin strips of filter paper with chemicals that changed colour based on the concentration of glucose present in the urine, the intensity of the resulting blue-green depending on the amount of peroxide, and hence, glucose, in the sample. ....

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Helen Murray Free, chemist who revolutionized diabetes testing, dies at 98

Helen Murray Free, chemist who revolutionized diabetes testing, dies at 98
Emily Langer
© J. Scott Applewhite/AP
Helen Murray Free receives the National Medal of Technology and Innovation from President Barack Obama.
When Helen Murray Free entered college in 1941, young women enjoyed few professional opportunities upon their graduation. For the most part, she said, they could hope to become “secretaries, nurses or teachers.” In keeping with the limitations of her time, Mrs. Free had enrolled at the College of Wooster in Ohio planning to become an English and Latin teacher.
But when the Japanese attacked Pearl Harbor, precipitating the U.S. entry into World War II, her horizons shifted. As young men emptied out of college campuses to join the armed forces, their seats in university science courses were suddenly vacant, although the country still needed scientists. ....

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House Democrats ramp up pressure on drug prices

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It’s Tuesday, welcome back to Prescription Pulse. John Oliver is the latest to take a look at the U.S. vaccination campaign. As always, send tips to David Lim ([email protected] or @davidalim). ....

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Helen Murray Free Dies at 98; Chemist Developed Diabetes Test

Helen Murray Free Dies at 98; Chemist Developed Diabetes Test
She and her husband invented a dip-and-read paper strip that greatly simplified the diagnosis of the disease and paved the way for home test kits.
Helen and Al Free at Miles Laboratories in Indiana (later acquired by Bayer). The paper-strip test they developed made it easier for clinicians to diagnose diabetes and cleared the way for home test kits.Credit.Bayer
By Denise Gellene
May 3, 2021, 3:08 p.m. ET
Helen Murray Free, a chemist who ushered in a revolution in diagnostic testing when she co-developed the dip-and-read diabetes test, a paper strip that detected glucose in urine, died on Saturday at a hospice facility in Elkhart, Ind. She was 98. ....

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