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Gene biomarkers indicate liver toxicity quickly, accurately ANI | Updated: Dec 19, 2020 23:53 IST
Washington [US], December 19 (ANI): A research team at the University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a few days while maintaining a high level of accuracy. The aim of this research was to identify the smallest set of indicators from the liver to predict toxicity and potential liver cancer, said Zeynep Madak-Erdogan, associate professor in the Department of Food Science and Human Nutrition at U of I and a lead author on the study. The agrochemical industry has a pipeline where they test new compounds in terms of toxicity-related endpoints. Liver toxicity is one of the most important endpoints, because the liver is the organ that receives the blood supply and cleans it, making it one of the biggest targets in terms of environmental toxic action, Madak-Erdogan said
Study identifies biomarker gene signature that indicates potential liver toxicity
When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal studies.
A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a few days while maintaining a high level of accuracy.
The aim of this research was to identify the smallest set of indicators from the liver to predict toxicity and potential liver cancer.
The agrochemical industry has a pipeline where they test new compounds in terms of toxicity-related endpoints. Liver toxicity is one of the most important endpoints, because the liver is the organ that receives the blood supply and cleans it, making it one of the biggest targets in terms of environmental toxic action.
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IMAGE: From left: University of Illinois researchers Zeynep Madak-Erdogan, associate professor of nutrition; Rohit Bhargava, director of the Cancer Center; and Colleen Bushell, director of the Healthcare Innovation Program Office at. view more
Credit: University of Illinois.
URBANA, Ill. ¬- When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal studies.
A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a few days while maintaining a high level of accuracy.