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Scientists Create Largest Atlas of Post-Zygotic Human Gene Mutations

Atlas could help to improve understanding of the genetic basis of cancer and other diseases caused by cellular malfunction, including aging. ....

United States , Harvard University , Nicole Rockweiler , Don Conrad , Washington University In St , Oregon Health Science University , School Of Medicine , Oregon National Primate Research Center , National Institute Of Health Genotype , Broad Institute Of Massachusetts Technology , Oregon Health , Science University , National Institute , Health Genotype Tissue Expression , Oregon National Primate Research , Washington University , Broad Institute , Massachusetts Institute ,

Identification of gene networks involved in uterine cancer could lead to better treatment options

No single gene causes uterine cancer, the fourth most common cancer among women, which is on the rise in the U.S. That’s why Clemson University ....

United States , Allison Hickman , Rini Pauly , Alex Feltus , Clemson University , National Institutes Of Health Genotype , College Of Science Department Genetics , Knowledge Independent Network Construction , Washington State University Assistant Professor Stephen Ficklin , American Cancer Society , Cancer Genome Atlas , National Institutes , Health Genotype Tissue Expression , Genes Genomes Genetics , Condition Specific Biomarker Systems , Yuqing Hang ,

Study identifies gene networks involved in uterine cancer that could be potential drug targets

No single gene causes uterine cancer, the fourth most common cancer among women, which is on the rise in the U.S. ....

United States , Allison Hickman , Alex Feltus , Emily Henderson , Clemson University , National Institutes Of Health Genotype , College Of Science Department Genetics , Knowledge Independent Network Construction , Washington State University Assistant Professor Stephen Ficklin , American Cancer Society , Cancer Genome Atlas , National Institutes , Health Genotype Tissue Expression , Uterine Cancer , Endometrial Cancer ,

RNA editing affects gene expression -- with disease implications

March 10, 2021 Researchers found that RNA editing events can have large downstream effects that influence gene expression and subsequent phenotypic manifestations of that expression. RNA editing may be a previously underappreciated mechanism driving human diseases, according to an analysis published in
RNA editing is a cellular process in which the sequence in mature RNA molecules is enzymatically altered from the genomic sequence. Altered levels of RNA editing have been associated with cancers and various other neurological conditions.
The most common RNA editing event in animals is adenosine (A) to an inosine (I) RNA editing, in which adenosines are deaminated to inosines. This A-to-I RNA editing is mediated by members of the adenosine deaminase acting on RNA (ADAR) family. ....

United States , Us National Institutes Of Health Genotype , Genome Biology , Genomic Medicine , Health Genotype Tissue Expression , Rna Editing , Adenosine Deaminase Acting On Rna , Quantitative Trait Loci Mapping , Rna Editing Quantitative Trait Loci Analysis , Genetic Polymorphisms , Phenotypic Variation , Rna Editing Sites , ஒன்றுபட்டது மாநிலங்களில் , மரபணு உயிரியல் , ர்ந திருத்துதல் , அளவு பண்பு லோகி விவரணையாக்கம் , ர்ந திருத்துதல் அளவு பண்பு லோகி பகுப்பாய்வு , ர்ந திருத்துதல் தளங்கள் ,

RNA editing affects gene expression -- with disease implications

RNA editing affects gene expression -- with disease implications
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