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Study identifies targetable fusion RNAs in breast cancer

Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

United statesSan antonioTodd golubNolan priedigkeitMass challenge team duncanShanklin foundationHarvard medical schoolSaverin breast cancer research fundCross family fund forBroad instituteDana farber cancer instituteAmerican association for cancer researchSan antonio breast cancer symposiumHuman cancer geneticsPan mass challengePan mass challenge team duncan

Technology Measures Function & Mobility in Homes of Older Cancer Patients

Technology Measures Function & Mobility in Homes of Older Cancer Patients
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Novobiocin Attacks BRCA-Mutated Cancer Cells from Within and Without, Study Shows

As the first clinical trial of the drug novobiocin is about to open for patients with cancers carrying BRCA gene mutations, new research at Dana-Farber Cancer Institute shows the drug poses a double threat to tumor cells.

Dana farber cancer instituteUnited statesBenz stangerGeoffrey shapiroGerburgm wulfAnitak mehtaAndrewj aguirreConstantia pantelidouBrianm wolpinJamesm clearyJenniferl guerrieroAland dandreaCarter grochalaHeta jadhavJeffrey patterson fortinLudwig center at harvard

Novobiocin Fights BRCA-Mutated Cancer Cells Inside and Out: Study

Novobiocin Fights BRCA-Mutated Cancer Cells Inside and Out: Study
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Gerburgm wulfJeffrey patterson fortinAndrewj aguirreConstantia pantelidouJamesm clearyCarter grochalaGeoffrey shapiroAnitak mehtaHeta jadhavBrianm wolpinBenz stangerJenniferl guerrieroAland dandreaBreast cancer research foundationNature communicationsUniversity of pennsylvania school medicine

Genetic Signature of Tumor Cells Predicts Response to Chemotherapy Drug for Patients with Form of Ovarian Cancer

Genetic Signature of Tumor Cells Predicts Response to Chemotherapy Drug for Patients with Form of Ovarian Cancer
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