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Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)

Selective vascular access to the brain is desirable in metabolic tracer, pharmacological and other studies aimed to characterize neural properties in isolation from somatic influences from chest, abdomen or limbs. However, current methods for artificial control of cerebral circulation can abolish pulsatility-dependent vascular signaling or neural network phenomena such as the electrocorticogram even while preserving individual neuronal activity. Thus, we set out to mechanically render cerebral hemodynamics fully regulable to replicate or modify native pig brain perfusion. To this end, blood flow to the head was surgically separated from the systemic circulation and full extracorporeal pulsatile circulatory control (EPCC) was delivered via a modified aorta or brachiocephalic artery. This control relied on a computerized algorithm that maintained, for several hours, blood pressure, flow and pulsatility at near-native values individually measured before EPCC. Continuous electroco ....

Harvard Biosciences , Leica Microsystems , Nihon Kohden , Rio National Instruments , Ohr Pharmaceuticals , Ge Healthcare , Ut Southwestern Medical Center , Labview National Instruments , Animal Research , Institutional Animal Care , Use Committee , Vivo Experiments , National Instruments , Bard Medical , Sodium Chloride , Native Doppler Measured , Jenoptik Gryphax , Animal Care ,

Electrophoresis Market is Expected to Rake in Revenues Worth US$ 3.5 Bn by 2032-End

As per Future Market Insights’ latest industry analysis, Global demand for electrophoresis market is set to increase at a 4.7% CAGR from 2022 to 2032, with an estimated market value of around US$ 2.2 Bn as of 2022. As per Future Market Insights’ projections, reagents and consumables held about 48.7% of the global ma. ....

New York , United States , Analytik Jena , Harvard Biosciences , Academic Research Institutes , Helena Laboratories Corporation , Lonza Group , Perkinelmer Inc , Agilent Technologies , Pharma Biotech Companies , Merck Kga , Takara Bio Inc , Hoefer Inc , Research Expert , Sebia Group , Shimadzu Corporation , Bio Rad Laboratories Inc , Market Insights Inc , Merck Kgaa , Greater New York Chamber , Thermo Fisher Scientific Inc , Danaher Corporation , Future Market Insight , Bio Rad Laboratories , Takara Bio , Cleaver Scientific ,

Essex Bay Capital Announces Launch, and Closes Its First Platform Investment in Leading SaaS platform, Munetrix

Essex Bay Capital Announces Launch, and Closes Its First Platform Investment in Leading SaaS platform, Munetrix
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Yash Singh , Harvard Biosciences , Franklin Foster , Jackie Lucas , Essex Bay Capital , Essex Bay , West Coasts , Managing Director , Audax Private Equity , Executive Vice President , Medtech Breakthrough Award , Michigan Datahub , Buzz Brown , Vera Voce ,