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Article In Brief In the wake of blood-clotting disorders in six young women who had been vaccinated with the single Johnson & Johnson COVID-19 vaccine, neurovascular neurologists and hematologists address questions about assessing risks and managing the side effects. Neurologists are getting queries from anxious patients in the aftermath of a nationwide “temporary” pause in administration of the single-shot Janssen/Johnson & Johnson COVID-19 vaccine. As of April 12, more than 6.8 million doses of the Janssen vaccine were administered around the country. Two days later, it climbed to 7.2 million doses. The pause, requested by both the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) on April 13, came in the wake of reports that six young women, ages 18 to 48, had developed serious blood clotting problems after receiving the vaccine. At press time, one woman had died, four others had not recovered yet, and one woman was discharged home.

United kingdomUnited statesSouth africaJennifer armstrongJanet woodcockAaran mareeMary cushmanGustavo saposnikHenryh bernsteinAvindra nathJanssen johnsonStephan mayerCenters for diseaseWestchester health networkUniversity of vermont medical centerAgency response