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Frail patients with atrial fibrillation who were switched to a newer NOAC agent had more bleeding than those left on older vitamin K antagonists, without any benefit in terms of thromboembolic events. ....
The risk of bleeding increased by about 60% in the oldest and frailest patients who were shifted from a VKA compared to those who stayed on the conventional medication.A new study presented at the. ....
Switching vitamin K antagonist (VKA) treatment to a non-vitamin K antagonist oral anticoagulant (NOAC) in frail elderly patients with atrial fibrillat.. ....