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Research: Varied COVID-19 Risk Among Immunocompromised Patients

Research: Varied COVID-19 Risk Among Immunocompromised Patients
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Virologic Rebound Occurs in ~20 Percent Receiving Nirmatrelvir-Ritonavir

Virologic rebound more common among those who started therapy within 2 days of symptom onset ....

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One in five patients experience rebound COVID after taking Paxlovid, new study finds

One in five patients experience rebound COVID after taking Paxlovid, new study finds
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One in five patients experience rebound COVID

<p>A new study by investigators from <a href="https://www.massgeneralbrigham.org/">Mass General Brigham</a> found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test—a phenomenon known as virologic rebound. By contrast, people not taking Paxlovid only experienced rebound about 2 percent of the time. Results are published in <a href="https://www.acpjournals.org/journal/aim/authors1"><em>Annals of Internal Medicine</em></a>.</p>
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Harvard University , United States , Shruti Sagar , Manishc Choudhary , Sarahp Hammond , Mark Siedner , Mamadou Barry , Yumeko Kawano , Zachary Wallace , Rockib Uddin , Gregorye Edelstein , Jacobe Lemieux , Dessie Tien , Rebeccaf Gilbert , Jonathon Li , Zahra Reynolds , Yijia Li , Amyk Barczak , Harvard Medical School , National Institute Of Arthritis , Harvard University Center , Massachusetts Consortium For Pathogen Readiness , Ragon Institute , National Institutes Of Health , Llura Gund Award For Rheumatoid Arthritis Research , Julie Boucau Ragon Institute ,

One in five patients experience rebound COVID after taking Paxlovid

One in five patients experience rebound COVID after taking Paxlovid
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Harvard University , United States , Gregorye Edelstein , Dessie Tien , Jacobe Lemieux , Jonathon Li , Rockib Uddin , Mark Siedner , Manishc Choudhary , Sarahp Hammond , Shruti Sagar , Mamadou Barry , Zahra Reynolds , Amyk Barczak , Yumeko Kawano , Rebeccaf Gilbert , Yijia Li , Zachary Wallace , Department Of Medicine , Massachusetts Consortium For Pathogen Readiness , Harvard University Center , Llura Gund Award For Rheumatoid Arthritis Research , Variants Program , Division Of Infectious Diseases , Public Health Solutions , National Institutes Of Health ,