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Discovery of cellular uptake pathway for larger molecules can be harnessed to create new drugs

A fundamental challenge in drug development is the balance between optimizing a drug's lock-and-key fit with its target and the drug's ability to make its way across the cellular membrane and access that target. ....

Luke Gilbert , Kevan Shokat , Kevin Lou , Emily Henderson , Discovery Industry Focus , Goldberg Benioff Endowed Professorship , Prostate Cancer Translational Biology , Small Molecules ,