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China NMPA Approves Phase III Clinical Trial of ASC40 Combined with Bevacizumab for Treatment of Patients with Recurrent Glioblastoma


China NMPA Approves Phase III Clinical Trial of ASC40 Combined with Bevacizumab for Treatment of Patients with Recurrent Glioblastoma
Phase III trial will evaluate progression-free survival and overall survival of patients with recurrent glioblastoma
Glioblastoma has an incidence rate of approximately 2.85 to 4.56 per 100,000 population per year in China, suggesting approximately 40,000 to 64,000 new cases of glioblastoma per year. More than 90% glioblastoma patients will relapse after surgery, radiation and chemotherapies
This is the first Phase III trial of ASC40 as a first-in-class drug candidate targeting tumor lipid metabolism
Phase II data of patients with recurrent glioblastoma have shown that the overall response rate for ASC40 plus Bevacizumab treatment was 65% including a complete response of 20% and a partial response of 45% ....

United States , Hong Kong , United Kingdom , Wenbin Li , Jinzij Wu , Tumor Treatment Center , Capital Medical University , Ascletis Pharma Inc , China National Medical Products Administration , Hong Kong Stock Exchange , Prnewswire Ascletis Pharma Inc , Glioma Committee Of Chinese Cancer Association , Vice Chairman , Secretary General , Glioma Committee , Chinese Cancer Association , Comprehensive Tumor Treatment Center , Beijing Tiantan Hospital , ஒன்றுபட்டது மாநிலங்களில் , ஹாங் காங் , ஒன்றுபட்டது கிஂக்டம் , மூலதனம் மருத்துவ பல்கலைக்கழகம் , ஹாங் காங் ஸ்டாக் பரிமாற்றம் , துணை தலைவர் , செயலாளர் ஜநரல் ,