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Cureus | The Prediction of Outcomes in Patients Admitted With Traumatic Brain Injury Using the Rotterdam Score

Objective: The objective was to use the Rotterdam score, which is based on a CT scan, to assess the outcomes of traumatic brain injury patients.

Material and Methods: This research, which included 319 head trauma patients, was carried out at the neurosurgery department of a tertiary care hospital between June 2019 and December 2020. The Rotterdam score was calculated for each patient on the basis of the first CT scan after the head injury. The Glasgow Outcome Score was used to assess the results three months following the injury.

Results: In our research, there were 270 male patients (84.6%) and 49 female patients (15.4%). The mean age was 37.4 ± 15.4 years and road traffic accidents were observed in 275 people (86.2%). Severe traumatic brain injury (TBI) was seen in 123 patients (38.6%). The most common Rotterdam score was 2 in 86 (27.0%) patients, while it was score 3 in 72 (22.6%), score 4 in 59 (18.5%), score 5 in 41 (12.9%), score 1 in 31 (9.7%) and score 6 in ....

New York , United States , Glasgow Outcome Score , Glasgow Coma Scale , Coma Scale , Glasgow Outcome Scale ,

Cureus | Role of Serum Homocysteine and Outcome in Patients With Traumatic Brain Injury

Background

There have been indications of a correlation between serum homocysteine (Hcy) levels and poor patient outcomes in traumatic brain injury (TBI). Thus, we aimed to explore the role of serum Hcy in influencing the outcome post TBI.

Methods

A case-control study was conducted at Liaquat University of Medical and Health Sciences (LUMHS) between January 15, 2022 and July 1, 2022. All patients between the ages of 18 and 75 years who presented with TBI, irrespective of severity, were included in the study. All patients with neurological disorders and infections, including but not limited to cerebral tuberculosis, Alzheimer's disease, epilepsy, brain cancer, Parkinson's, and stroke, were excluded from the study. For comparison, healthy controls with similar demographics were enrolled in the study. All patients and controls underwent biochemical evaluation of serum Hcy and neurological assessment at presentation. In addition, all sociodemographic and ....

Hyperhomocysteinemia Hhcy , Health Sciences , Liaquat University , Glasgow Outcome Score , Glasgow Coma Score , Serum Hcy , Glasgow Coma Scale ,

vasopharm GmbH Announces Brain Lactate Microdialysate Data from Post Hoc Analyses of Clinical Trials in Traumatic Brain Injury

Ronopterin significantly reduces lactate levels in brain microdialysate from TBI patients reflecting energetic stability and neuroprotection during the early. ....

Glasgow City , United Kingdom , Harald Schmidt , Stefan Wolf , John Stover , Ulrich Walter , Department Of Neurosurgery Charit , Drug Monitoring Committee , International Neurotrauma Symposium , Neurosurgery Charit , Chief Medical Officer , Plenary Session , Abstract Lecture , Traumatic Brain Injury , Medical School , Clinical Biochemistry , Nitric Oxide Synthase , Glasgow Outcome Score , Therapy Intensity Level , Full Analysis Set , Glasgow Outcomes Scale , Good Recovery ,

vasopharm GmbH Announces Brain Glutamate Microdialysate Data from Post Hoc Analyses of Clinical Trials in Traumatic Brain Injury

Ronopterin significantly reduces glutamate levels measured in brain microdialysate from TBI patients, an important and long sought indicator of biochemical. ....

Glasgow City , United Kingdom , Baden Wüberg , Harald Schmidt , Andreas Unterberg , John Stover , Ulrich Walter , Carl Henrik Nordstr , Department Of Neurosurgery , Drug Monitoring Committee , University Hospital Heidelberg , Clinical Development Plan , Odense University Hospital , Professor Andreas Unterberg , Lead Investigator , Chief Medical Officer , Traumatic Brain Injury , Medical School , Clinical Biochemistry , Nitric Oxide Synthase , Glasgow Outcome Score , Therapy Intensity Level , Full Analysis Set , Glasgow Outcomes Scale , Good Recovery ,

vasopharm GmbH Announces Post Hoc Analyses of Clinical Trials in Traumatic Brain Injury

/PRNewswire/ vasopharm GmbH ("vasopharm"), a privately-held biopharmaceutical company focusing on novel therapeutics to treat cerebrovascular diseases,. ....

Glasgow City , United Kingdom , Harald Schmidt , John Stover , Ulrich Walter , Erich Schmutzhard , University Of Innsbruck , Drug Monitoring Committee , Clinical Development Plan For Ronopterin , Clinical Development Plan , Medical University , Chief Investigator , Glasgow Outcome Scale , Unfavorable Outcome , Favorable Outcome , Good Recovery , Intensity Level , Chief Medical Officer , Traumatic Brain Injury , Medical School , Clinical Biochemistry , Nitric Oxide Synthase , Glasgow Outcome Score , Full Analysis Set , Glasgow Outcomes Scale ,