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Prosthetic valve endocarditis (PVE) was rare after transcatheter aortic valve replacement (TAVR) in low-risk patients, but when it did occur, the complication was associated with substantial morbidity and mortality, according to investigators from the Low Risk TAVR (LRT) study.
Incidence of PVE was 1.5% within 1 year (zero within 30 days) and 2.8% after 1 year based on an analysis of 396 low-risk TAVR recipients.
Survival was 100% in early endocarditis, but only 67% in late endocarditis, reported Giorgio Medranda, MD, of MedStar Washington Hospital Center in Washington, D.C., during the virtual meeting of the Society for Cardiovascular Angiography and Interventions (SCAI).
Of the 11 patients with PVE, the three who underwent surgical aortic valve reintervention survived. Six patients suffered embolic strokes, two of whom died after antibiotic treatment alone. These two deaths were associated with valve endocarditis, both occurring after day 500, caused by meth