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Top in women's health: Alzheimer's disease vulnerability; ozone exposure during pregnancy

Developing menopause at an earlier age and late initiation of hormone therapy were associated with increased vulnerability to Alzheimer’s disease, according to researchers. “Female individuals who experience younger age at menopause may represent a subgroup for priority inclusion in Alzheimer’s disease prevention trials,” Gillian T. Coughlan, MS, PhD, a research fellow in ....

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Women Have Higher Tau, Especially in Setting of Elevated Aβ

WEDNESDAY, April 5, 2023 (HealthDay News) Women have higher tau than men, especially those with elevated amyloidβ (Aβ), according to a study published online April 3 in JAMA Neurology. Gillian T. Coughlan, Ph.D., from Massachusetts General Hospital in Boston, and colleagues examined the extent to which sex, age at menopause, and hormone therapy use ....

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Early Menopause May Increase Risk of Alzheimer's Disease

Research conducted by Mass General Brigham supports clinical guidelines that indicate starting hormone therapy is safer when started close to the onset of menopause. Women have a higher likelihood of developing Alzheimer's disease (AD) compared to men, comprising two-thirds of the individuals aff ....

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Earlier age at menopause, later HT initiation linked to Alzheimer's disease vulnerability

Being younger at menopause onset and initiating hormone therapy after more than 5 years were both linked to increased tau vulnerability among women, according to a cross-sectional study published in JAMA Neurology.“Early trials and observational studies suggest that use of exogenous hormones, via HT, may ameliorate cognitive impairment in menopausal or postmenopausal individuals,” ....

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