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Microbial Control And Monitoring In Aseptic Processing Cleanrooms


Microbial Control And Monitoring In Aseptic Processing Cleanrooms
By Gilbert Dalmaso
Cleanrooms and associated controlled environments provide contamination control (inert particles and microbiological entities) to levels appropriate for accomplishing  contamination-sensitive activities. Products and processes that benefit from the control of contamination include those in such industries as aerospace, electronics, food and beverages, cosmetics, general healthcare and medical devices, and pharmaceutical products requiring a variety of clean environments.
Environmental Monitoring (EM), particularly in pharmaceutical manufacturing facilities where the risk of microbial contamination is controlled through aseptic processing, comprises both physical and microbiological test methods. It is a common assumption that if fewer total particulates are present in a cleanroom, it is less likely that airborne microorganisms will be present. This is true only if human operators are ....

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