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Advanced Gene Editing Method Can Power the Next Generation of Cell and Gene Therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach could also power the development of advanced cell therapies for ca ....

United States , E John Wherry , Rahul Kohli , Barbara Schiffrin , Franke Weise , Junwei Shi , Gerd Blobel , Shelleyl Berger , Abramson Family Cancer Research Institute , Food Drug Administration , Daniels Och University Professor In Cell , University Of Pennsylvania , Penn Epigenetics Institute , Perelman School Of Medicine , Perelman School , Nature Biotechnology , Penn Medicine , Drug Administration , Barbara Schiffrin President , Distinguished Professor , Systems Pharmacology , Translational Therapeutics , University Professor , Developmental Biology , Penn Epigenetics , Cancer Biology ,

Improved gene editing method could power the

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach could also power the development of advanced cell therapies for cancers and other diseases, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania. ....

United States , University Of Pennsylvania , Gerd Blobel , Barbara Schiffrin , Shelleyl Berger , Junwei Shi , E John Wherry , Franke Weise , Rahul Kohli , Food Drug Administration , National Institute Of Health , Abramson Family Cancer Research Institute , Method Of Research , Perelman School Of Medicine , Daniels Och University Professor In Cell , Parker Institute For Cancer Immunotherapy , Penn Epigenetics Institute , Perelman School , Nature Biotechnology , Penn Medicine , Drug Administration , Barbara Schiffrin President , Distinguished Professor , Systems Pharmacology , Translational Therapeutics , University Professor ,

Gene Editing Method Could Power New Cell Gene Therapies

Gene Editing Method Could Power New Cell Gene Therapies
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United States , Shelleyl Berger , E John Wherry , Gerd Blobel , Junwei Shi , Franke Weise , Rahul Kohli , Barbara Schiffrin , Abramson Family Cancer Research Institute , Penn Epigenetics Institute , University Of Pennsylvania , Food Drug Administration , Parker Institute For Cancer Immunotherapy , Daniels Och University Professor In Cell , Perelman School Of Medicine , National Institute Of Health , Perelman School , Nature Biotechnology , Penn Medicine , Drug Administration , Barbara Schiffrin President , Distinguished Professor , Systems Pharmacology , Translational Therapeutics , University Professor , Developmental Biology ,

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. ....

United States , Gerd Blobel , Barbara Schiffrin , Franke Weise , Junwei Shi , E John Wherry , Rahul Kohli , Shelleyl Berger , Emily Henderson , Perelman School Of Medicine , University Of Pennsylvania , Penn Epigenetics Institute , Daniels Och University Professor In Cell , Abramson Family Cancer Research Institute , Food Drug Administration , Perelman School , Nature Biotechnology , Penn Medicine , Drug Administration , John Wherry , Barbara Schiffrin President , Distinguished Professor , Systems Pharmacology , Translational Therapeutics , University Professor , Developmental Biology ,

Fulcrum Therapeutics® Announces Additional HBG mRNA Induction from Higher Dose Cohorts in Phase 1 Healthy Adult Volunteer Trial of FTX-6058 for Sickle Cell Disease and New Preclinical Mechanism Data

Achieved mean 5.6-fold HBG mRNA induction at 20mg and mean 6.2-fold at 30mg after 14 days of once-daily dosing, further supporting potential of FTX-6058 to provide a functional cure Continues to be. | December 6, 2021 ....

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