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Treatment Combo Shows 'Clinical Benefit' in Liver Cancer Trial

The combination of a tyrosine kinase inhibitor with an immune checkpoint inhibitor significantly improved progression-free survival in patients with hepatocellular carcinoma, shows a new study. ....

United States , San Francisco , Lorenza Rimassa , Robin Kate Kelley , University Of California , Humanitas University , Lancet Oncology , Hepatocellular Carcinoma , Liver Cancer , Hepatocellular Cancer , Ancer Liver , Ancer Hepatocellular , Biologic Therapy , Malignant Kidney Neoplasm , Kidney Cancer , Renal Cell Cancer , Renal Cell Carcinoma , Ancer Kidney , Ancer Renal Cell , Tyrosine Kinase Inhibitor , Gastrointestinal Hemorrhage , Gastrointestinal Bleeding ,

Are Pain Meds the Only Option for Chronic Pain in Cirrhosis?

The first treatment option for any pain should be self-directed, nonpharmacologic interventions. ....

Ann Arbor , United States , Paul Martin , University Of Miami , Fibromyalgia Survey Criteria , University Of Michigan , Survey Criteria , Neuropathic Pain Questionnaire , Spain Guide , Pain Management , Pain Management , Biliary Disease , Allbladder Disease , Chronic Pain , Physical Medicine And Rehabilitation , Physical Therapy , Acute Pain , Hepatic Encephalopathy , Portal Systemic Encephalopathy , Ortosystemic Encephalopathy , Gastrointestinal Hemorrhage , Gastrointestinal Bleeding , Leeding Gastrointest ,

Peptic Ulcer Risk in New Users of Low-Dose Aspirin

New research finds a significantly increased risk for gastric and duodenal ulcers among adults starting low-dose aspirin therapy but not among peers who have been taking low-dose aspirin for some time. ....

United States , Baden Wüberg , Ashwin Ananthakrishnan , Harvard Medical School , German Cancer Research Center , Ben Sch , Alimentary Pharmacology , United Kingdom Biobank , Massachusetts General Hospital , Medscape Medical , Gastrointestinal Hemorrhage , Gastrointestinal Bleeding , Leeding Gastrointestinal , Duodenal Ulcer , Peptic Ulcer Disease , Lcer Peptic , Gastric Ulcer , Nonsteroidal Anti Inflammatory Drugs Nsaids , Nonsteroidal Anti Inflammatory Drugs , Rug Nonsteroidal Anti Inflammatory , Pain Management , Pain Management ,

Pseudocirrhosis in Breast Cancer May Signal Liver Metastases

A large case series of metastatic breast cancer patients with pseudocirrhosis found that almost all such patients had hormone receptor–positive disease as well as extensive liver metastases. ....

United States , San Francisco , Laura Huppert , University Of California , American Society Of Clinical Oncology , American Society , Metastatic Breast Carcinoma , Breast Cancer , Alignant Breast Neoplasm , Hepatocellular Carcinoma , Liver Cancer , Hepatocellular Cancer , Ancer Liver , Ancer Hepatocellular , Malignant Secondary Liver Neoplasm , Etastasis Liver , Biliary Disease , Allbladder Disease , Esophageal Varices , Gastrointestinal Hemorrhage , Gastrointestinal Bleeding , Leeding Gastrointestina ,

Sex-Adjusted Liver Allocation Scoring Tool Would Improve Transplant Equity

Females on the liver transplant waiting list are disadvantaged by the sodium-adjusted Model for End-stage Liver Disease score (MELDNa) currently employed to guide allocation decisions, but a sex-adjusted MELDNa score would help address the inequity and decrease mortality for both sexes, researchers say. ....

United States , Vanderbilt University , Jayme Locke , Brittany Shelton , Julia Sealock , University Of Alabama , Vanderbilt University Medical Center , Reuters Health , End Stage Liver Disease , Biliary Disease , Allbladder Disease , Transplantation Liver , Epatic Transplantation , Ransplantation Hepatic , Liver Transplantation , Hepatic Encephalopathy , Liver Disease , Portal Systemic Encephalopathy , Ortosystemic Encephalopathy , Gastrointestinal Hemorrhage , Gastrointestinal Bleeding , Leeding Gastrointestinal , Liver Failure , Hepatic Failure , Transplant Wait ,