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Alcohol and health – Authors' reply

In our analysis,1 we estimated the theoretical minimum risk exposure level (TMREL)
and the non-drinker equivalence of alcohol use, using a new approach to weight relative
risk (RR) curves by estimated disability-adjusted life-years (DALYs) in every region,
age, sex, and year. This differed from our previous research where we used global
DALYs to estimate alcohol risk. Our current analysis showed that the TMREL increases
with age and varies across regions, ranging from zero to two standard drinks per day. ....

Jakob Manthey , Mika Kivim , Gabrielm Leung , Elsevier Ltd , Global Burden , Disease Study , Kevin Shield ,