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April 28, 2021
For patients with heart failure who require cardiac resynchronization therapy (CRT) to correct left bundle branch block (LBBB), His-bundle pacing may be a feasible alternative to traditional biventricular pacing, a pilot randomized trial suggests.
His-CRT was possible in 72% of patients and provided improvements in echocardiographic parameters, symptoms, and physical function similar to those seen with biventricular-CRT, albeit with higher pacing thresholds, Michael Vinther, MD, PhD (The Heart Centre, Rigshospitalet, Copenhagen, Denmark), reported at the virtual European Heart Rhythm Association (EHRA) Congress 2021.
The trial was limited by its small size (50 patients) and its conduct at a single center, but “we are confident to say that His-CRT holds promise as an alternative to biventricular pacing in selected heart failure patients,” Vinther concluded. “And we hope that our study, among others, can pave the way for a larger randomized study that can establ