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Achilles Therapeutics Strengthens Scientific Advisory Board with Appointment of Alena Gros, Ph.D. and Ben Creelan, M.D.

Achilles Therapeutics Strengthens Scientific Advisory Board with Appointment of Alena Gros, Ph.D. and Ben Creelan, M.D.
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Achilles Therapeutics PLC: Achilles Therapeutics Strengthens Scientific Advisory Board with Appointment of Alena Gros, Ph.D. and Ben Creelan, M.D.

Internationally recognized experts bring extensive scientific and clinical research expertise in cancer immunology and immunotherapyLONDON, Feb. 07, 2022 (GLOBE NEWSWIRE) Achilles Therapeutics plc (NASDAQ: ....

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Achilles Therapeutics Strengthens Scientific Advisory Board

Internationally recognized experts bring extensive scientific and clinical research expertise in cancer immunology and immunotherapy. ....

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Study reveals how cancer cells escape death by lymphocytes

Study reveals how cancer cells escape death by lymphocytes
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The unveiling of a novel mechanism of resistance to immunotherapy targeting HER2

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IMAGE: Joaquín Arribas, co-Program Director of Preclinical and Translational Research at VHIO, ICREA Professor, CIBERONC Investigator, Director of the Hospital del Mar Medical Research Institute (IMIM).
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Credit: VHIO
Redirection of lymphocytes, via T-cell bispecific antibodies (TCBs) and chimeric antigen receptors (CARs), is already approved to treat some hematologic malignancies. In solid tumors these immune-based strategies continue to fail.
Research led by Joaquín Arribas, co-Program Director of Preclinical and Translational Research at VHIO, has now shown how HER2 breast cancer cells adopt a strategy to resist clearance by redirected lymphocytes. Findings evidence that the disruption of interferon-gamma signaling confers resistance to these immunotherapies and promotes disease progression. ....

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