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Spectrum: New Peers Review takes on neurodegeneration CBD is less psychoactive than THC. In fact, CBD may even reduce the psychoactive elements in THC. CBD has antidepressant and anti-inflammatory characteristics. Cannabidiol is not to be mistaken for cannabinol (CBN). CBN was the first cannabinoid to be detected. As with CBD, CBN has anti-inflammatory properties. Binding to the body Cannabinoids also exist naturally in our bodies. They are called endocannabinoids and are part of the endocannabinoid system, which allows phytocannabinoids, those derived from plants, to affect us. THC, for instance, binds to CB1 cannabinoid receptors in the brain, and that starts a process that releases its psychoactive effect. ....