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The use of atorvastatin (Lipitor) did not reduce cartilage volume loss in patients with knee osteoarthritis (OA) over a period of 2 years, a placebo-controlled study found.
Among patients randomized to receive atorvastatin, 40 mg per day, the reduction of tibial cartilage volume was 1.66% per year, while for those given placebo, the reduction was 2.17%, for a between-group difference of 0.50% (95% CI -0.17 to 1.17,
P=0.14), reported Flavia M. Cicuttini, PhD, of Monash University in Melbourne, Australia, and colleagues.
These findings do not support the use of atorvastatin as a disease-modifying agent in established knee OA, the researchers concluded in their study online in ....

South Australia , Flaviam Cicuttini , Monash University , Western Ontario , Mcmaster Universities Osteoarthritis Index , தெற்கு ஆஸ்திரேலியா , மோனாஷ் பல்கலைக்கழகம் , மேற்கு ஆஂடேரியொ , மக்மாஸ்டர் பல்கலைக்கழகங்கள் ஆஸ்டியோவார்த்ரைடிஸ் குறியீட்டு ,