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A history of heavy drinking increases vulnerability to, and the severity of, Alzheimer’s Disease (AD) and related dementias, with Alcohol Use Disorder (AUD) identified as the strongest modifiable risk factor for early-onset dementia. Heavy drinking has increased markedly in women over the past 10 years, with mature adult women reporting a 41% increase in heavy drinking days during the coronavirus (COVID-19) pandemic. This raises concern over the impact of excessive alcohol consumption during mature adulthood on dementia-related outcomes in both the short- and long-term. As a first pass attempt at addressing this issue, the present study employed isogenic and congenic female and male mature adult (5-9 months of age) C57BL/6J (B6J) mice to examine how a 1-month history of alcohol intake under modified Drinking-in-the-Dark (DID) procedures (10, 20,40% alcohol v/v) alters spatial and working memory. In both a genetically and experientially heterogeneous cohort of mice and in an isogenic ....
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it s like that movie. remember that okay. i ll stop reminiscing here. we ll get back to it later. . > well, after so much criticism about the way that the military is addressing mental health issues, the u.s. army is ordering a major medical review. all post-traumatic stress disorder cases involving army thldiers since 2001 are going to be evaluated. and that s after complaints about doctors reversing their decisions about soldiers diagnosed with ptsd. the army promises to correct such decisions and provide proper mental health care to soldiers. they deserve it. that s for sure. the nation s top autism experts have announced they have broken some new ground. they say there is a very simple way to find some warning signs in children as young as just 6 months. abc s medical editor dr. richard besser has more. reporter: babies can tell you a lot. without speaking a word. watch his head a benjamin s 6 months old. i m going to do the head lag test. watch his head as i pull his ull ....