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#VisualAbstract: Once-a-month fitusiran reduces bleeding rates in patients with hemophilia A and B with inhibitors

1. Annualized bleeding rate was reduced by 91% in the fitusiran prophylaxis group compared to the bypassing agents on-demand group. 2. 5% of patients in the fitusiran group reported thromboembolic events; there were no deaths. Evidence Rating Level: 1 (Excellent) Study Rundown: Hemophilia is marked by a deficiency in certain coagulation factors that make patients prone ....

Study Rundown ,

Once-a-month fitusiran reduces bleeding rates in patients with hemophilia A and B with inhibitors

1. Annualized bleeding rate was reduced by 91% in the fitusiran prophylaxis group compared to the bypassing agents on-demand group. 2. 5% of patients in the fitusiran group reported thromboembolic events; there were no deaths. Evidence Rating Level: 1 (Excellent) Study Rundown: Hemophilia is marked by a deficiency in certain coagulation factors that make patients ....

Rating Level , Efanesoctocog Alfa Prophylaxis , Severe Hemophilia , Between Feb , Hemophilia A , Hemophilia B , Major Bleeding , Chronic Disease ,

Sanofi - Aventis Groupe: Press Release: Two fitusiran Phase 3 studies published in The Lancet and The Lancet Haematology highlight potential to address unmet needs across all types of hemophilia

Two fitusiran Phase 3 studies published in The Lancet and The Lancet Haematology highlight potential to address unmet needs across all types of hemophilia Both Phase 3 studies achieved their primary ....

Tarik Elgoutni , Nicolas Obrist , Felix Lauscher , Sandrine Guendoul , Dietmar Berger , Nathalie Pham , Corentine Driancourt , Sally Bain , Eva Schaefer Jansen , Alnylam Pharmaceutical Inc , Lancet Haematology , Chief Medical Officer , Alnylam Pharmaceutical , Private Securities Litigation Reform Act , Statement Regarding Forward Looking ,

Sanofi - Aventis Groupe: Press Release: Fitusiran prophylaxis reduced bleeds by 61% in people with hemophilia A or B, with or without inhibitors, compared to prior factor or bypassing agent prophylaxis

Fitusiran prophylaxis reduced bleeds by 61% in people with hemophilia A or B, with or without inhibitors, compared to prior factor or bypassing agent prophylaxis A median annualized bleeding rate ....

Tel Aviv , Eva Schaefer Jansen , Corentine Driancourt , Felix Lauscher , Nathalie Pham , Sally Bain , Gili Kenet , Priya Nanduri , Global Head Of Development , International Society On Thrombosis , Alnylam Pharmaceutical Inc , International Society , Israeli National Hemophilia Center , Sheba Medical Center , Amalia Biron Thrombosis Research Institute , Tel Aviv University , Chief Medical , On Demand Factor Concentrates , Bypassing Agents , Breakthrough Bleeds , Two Phase , Targeting Antithrombin , Antithrombin Levels , Thrombin Generation , Alnylam Pharmaceutical , Private Securities Litigation Reform Act ,

Sanofi - Aventis Groupe: Data from two Phase 3 studies demonstrating fitusiran significantly reduced bleeds in people with hemophilia A or B, with or without inhibitors, were featured at ASH's plenary and late-breaking sessions

Data from two Phase 3 studies demonstrating fitusiran significantly reduced bleeds in people with hemophilia A or B, with or without inhibitors, were featured at ASH's plenary and late-breaking ....

France General , United States , Eva Schaefer Jansen , Arnaud Delepine , Felix Lauscher , Nathalie Pham , Dietmar Berger , Sally Bain , American Society Of Hematology , Global Head Of Development , Alnylam Pharmaceutical Inc , American Society , Late Breaking Abstract Session , Plenary Scientific Session , Global Head , Alnylam Pharmaceutical , Private Securities Litigation Reform Act , Statement Regarding Forward Looking ,