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Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12 – an essential nutrient that supports healthy development and functioning of the central nervous system (CNS) – and multiple sclerosis (MS), a chronic disease in which the body's immune system attacks the CNS and which can produce neurodegeneration. ....

New York , United States , Jerold Chun , Sanford Burnham Prebys , Yasuyuki Kihara , Life Sciences , Juntendo University , Tokyo University Of Pharmacy , University Of Southern California , University Of New York , Cell Reports , Southern California , Tokyo University , State University , Multiple Sclerosis , Vitamin B12 , Animal Model , Central Nervous System , Chronic Disease , Immune System , Nervous System , Vision Loss , Vitamin B ,

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) that affect the gastrointestinal tract. ....

Lily Ramsey , International Organisation , Inflammatory Bowel Diseases , Selecting Therapeutic Targets , Inflammatory Bowel Disease , Cell Adhesion , Ulcerative Colitis ,

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Researchers pursued insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of MS. ....

Underhilstudio Shutterstock , International Cognitive Assessment , Translational Psychiatry , Image Credit , Beck Depression Inventory , Brief International Cognitive Assessment , Symbol Digit Modalities Test , White Matter , Multiple Sclerosis , Clinical Depression , Depressive Disorder , Magnetic Resonance Imaging , Major Depressive Disorder ,

Research reveals a more effective treatment for multiple sclerosis patients

Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's disease or Huntington's disease that affect roughly 2.8 million people in the world. ....

United States , Baylor College Of Medicine , Oguz Kanca , Sudhir Gopal Tattikota , Hyun Kyoung Lee , Nobert Perrimon , Emily Henderson , Shenzhao Lu , Zhongyuan Zuo , Hyunglok Chung , Hugoj Bellen , Dan Duncan Neurological Research Institute , Warren Alpert Foundation , National Institutes Of Health , Multiple Sclerosis , Cell Metabolism , Texas Children , Baylor College , Very Long Chain Fatty Acids , Acid Elongase , Hye Jin Park , Jung Wan Mok , Hyun Kyoung , National Institutes , Dan Duncan Neurological Institute , Lzheimer 39s Disease ,

Novartis plans to petition the U.S. Supreme Court to uphold validity of the Gilenya® (fingolimod) dosing regimen patent

Ad hoc announcement pursuant to Art. 53 LR Basel, 21 September, 2022 Today, Novartis announced that the U.S. Court of Appeals for the Federal Circuit (CAFC) ....

United States , Exchange Commission , Us Supreme Court , Us Court , Us District Court , Year Guidance For Group , Federal Circuit , Abbreviated New Drug Application , Year Guidance ,