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In search of active substances against stress-related diseases

In search of active substances against stress-related diseases
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Felix Hausch , Thomasm Geiger , Thomas Geiger , Angewandte Chemie , Sarah Engel , Department Of Chemistry , Nature Structural , Molecular Biology , Synthetic Biology , Asat Baischew , Proteolysis Targeting Chimeras ,

Wie Hessen unkonventionelle Forschung unterstützen will

Wie Hessen unkonventionelle Forschung unterstützen will
faz.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from faz.net Daily Mail and Mail on Sunday newspapers.

Tobias Hagen , Felix Hausch , Achim Schmidtko , Max Karl , Robert Karel , Programme Of Loewe , Technical University Darmstadt , Trojan Horse Will , Links Well , Which They , Attackers Used , Been Active , Projects Receive , Tuesday Hessian Angela Thorn , New Programme , Exzellenz Initiative Loewe , Deputy Coordinator , Care Normally , How Important , Viruses Usually Side , Langen Drives , Key Question , Trojan Horse , System Shut , Been Developed , Two Scientists ,

Researchers identify new approach to clear toxic Huntingtin protein

Researchers world-wide are focused on clearing the toxic mutant Huntingtin protein that leads to neuronal cell death and systemic dysfunction in Huntington's disease (HD), a devastating, incurable, progressive neurodegenerative genetic disorder. ....

Barbara Bailus , Felix Hausch , Lisa Ellerby , Buck Institute Ellerby , Technical University In Darmstadt , Buck Institute , Keck Graduate Institute In Claremont , Study Director , Assistant Professor , Keck Graduate Institute , Technical University , Ell Death , Genetic Disorder , Huntington 39s Disease , தொழில்நுட்ப பல்கலைக்கழகம் இல் டர்ம்ஸ்டட்ட் , பக் நிறுவனம் , கேக்க் பட்டதாரி நிறுவனம் இல் கிளாரிமாண்ட் , படிப்பு இயக்குனர் , உதவியாளர் ப்ரொஃபெஸர் , கேக்க் பட்டதாரி நிறுவனம் , தொழில்நுட்ப பல்கலைக்கழகம் ,

Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein

Recent failed clinical trials of a drug designed to clear the mutant Huntingtin protein that causes Huntington s disease (HD) heightens the need for new approaches for the devastating, incurable, progressive neurodegenerative genetic disorder. Scientists at the Buck Institute have found that the targeting the protein called FK506-binding protein 51 or FKBP51 promotes the clearing of those toxic proteins via autophagy, a natural process whereby cells recycle damaged proteins and mitochondria and use them for nutrition. ....

Jesse Simons , Swati Naphade , Michellee Ehrlich , Ningzhe Zhang , Kuruwitage Lakshika Madushani , Stephen Scheeler , Feliz Hausch , Technische Universitat Darmstadt , Kathrineh Schreiber , Jordi Creus Muncunill , Felix Hausch , Mariaa Sanchez , Alejandro Lopez Ramirez , Barbara Bailus , Brian Kennedy , Lisa Ellerby , Stanislav Moroz , Ashley Loureiro , Pioneer Grant Fund , Department Of Neurology , National Institutes Of Health , Other Buck Institute , Buck Institute Doublex Fellowship , Icahn School Of Medicine At Mount Sinai , Technical University In Darmstadt , Buck Institute Ellerby ,