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A high-resolution glimpse of gene expression in cells


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Courtesy of the researchers
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Using a novel technique for expanding tissue, MIT and Harvard Medical School researchers have devised a way to label individual molecules of messenger RNA within a tissue sample and then sequence the RNA.
This approach offers a unique snapshot of which genes are being expressed in different parts of a cell, and could allow scientists to learn much more about how gene expression is influenced by a cell’s location or its interactions with nearby cells. The technique could also be useful for mapping cells in the brain or other tissues and classifying them according to their function. ....

United Kingdom , Adam Marblestone , Daniel Goodwin , Asmamaw Wassie , John Doerr , Lisa Yang , Anubhav Sinha , George Church , Ed Boyden , Broad Institute , Ilan University , National Institutes Of Health , Harvard Medical School , National Science Foundation , Chan Zuckerberg Initiative Human Cell Atlas , Mcgovern Institute , Harvard University , Cancer Research United Kingdom , Howard Hughes Medical Institute , Stan Professor , Govern Institute , Shahar Alon , Bar Ilan University , Fei Chen Phd , National Institutes , Open Philanthropy Project ,