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Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials

This individual patient data meta-analysis showed that remdesivir reduced mortality
in patients hospitalised with COVID-19 who required no or conventional oxygen support,
but was underpowered to evaluate patients who were ventilated when receiving remdesivir.
The effect size of remdesivir in patients with more respiratory support or acquired
immunity and the cost-effectiveness of remdesivir remain to be further elucidated. ....

Nikki Rommers , Rosine Mucklow , Nina Khanna , Lars Hemkens , Marco Cattaneo , Fabrice Helfenstein , Stephan Schobinger , Benjamin Kasenda , International Clinical Trials Registry Platform , Gilead Sciences , Swiss National Science Foundation , Research Foundation Of The University Basel , Elsevier Ltd , Fonds De Recherche , Research Foundation ,