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Immunotherapy May Hold Promise for Skin Cancers After Kidney Transplant

Two studies had 'important differences,' but can help guide clinicians ....

United States , Dana Farber Cancer Institute , Evanj Lipson , Mike Bassett , Shlomoa Koyfman , Jessical Geiger , Glennj Hanna , Johns Hopkins University School Of Medicine , Clinical Oncology , Johns Hopkins University School , Cleveland Clinic , Clin Oncol ,

Biomarkers Found for Response to Kidney Cancer Immunotherapy

Biomarkers Found for Response to Kidney Cancer Immunotherapy
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Dana Farber Cancer Institute , United States , Memorial Sloan Kettering Cancer Center , New York , Beth Israel Medical Center , Michael Atkins , Evanj Lipson , Ezra Baraban , Robertj Motzer , Janis Taube , Saurabh Gupta , Tonik Choueiri , Bristol Myers Squibb , Jsd Johns Hopkins , Sabina Signoretti , Suzannel Topalian , David Mcdermott , Jaroslaw Jerdych , Ludmila Danilova , Michael Brigham , Akoya Biosciences , Julie Stein Deutsch , National Institutes Of Health , Dana Farber Harvard Cancer Center Kidney , Johns Hopkins University School Of Medicine , Tumor Microenvironment Laboratory ,

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict before treatment begins how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. ....

Dana Farber Cancer Institute , United States , Memorial Sloan Kettering Cancer Center , New York , Beth Israel Medical Center , Sabina Signoretti , Emily Henderson , Ezra Baraban , Michael Atkins , Jaroslaw Jerdych , Saurabh Gupta , David Mcdermott , Suzannel Topalian , Robertj Motzer , Tonik Choueiri , Janis Taube , Evanj Lipson , Ludmila Danilova , Julie Stein Deutsch , Bristol Myers Squibb , Bloomberg Kimmel Institute For Cancer Immunotherapy , Johns Hopkins Kimmel Cancer Center , Beth Israel Deaconess Medical Center , Tumor Microenvironment Laboratory , Division Of Dermatopathology , Georgetown Lombardi Comprehensive Cancer Center ,

FDA approves new immunotherapy treatment regimen for melanoma patients

The treatment was developed and studied by researchers at Johns Hopkins and targets aggressive forms of skin cancer ....

Suzannel Topalian , Johns Hopkins , Evanj Lipson , Byamy Monepublished , Melanoma Research Alliance To Johns Hopkins , Bloomberg Kimmel Institute For Cancer Immunotherapy , Johns Hopkins Kimmel Cancer Center , Cancer Immunology Program , Drug Administration , Bloomberg Kimmel Institute , Kimmel Institute , New England Journal , Melanoma Research Alliance , Johns Hopkins Kimmel Cancer ,

Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy

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IMAGE: The AstroPath platform allows for the assessment of the level of expression of a given marker on individual cells, while maintaining information on their spatial location. Shown here is.
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Credit: Seyoun Park, Ph.D.
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
A new platform, called AstroPath, melds astronomic image analysis and mapping with pathology specimens to analyze microscopic images of tumors. ....

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