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Early use of anakinra reduces risk of mortality for patients with COVID-19 pneumonia, reduces ICU admission and increases likelihood of full recovery


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- Day 28 full results from the SAVE-MORE study show early treatment with anakinra plus SOC (standard of care) reduced mortality by 55% and reduced average time until ICU (intensive care unit) discharge by four days
- Day 28 full results from the SAVE-MORE study show early treatment with anakinra plus SOC (standard of care) reduced mortality by 55% and reduced average time until ICU (intensive care unit) discharge by four days
- In patients treated with anakinra plus SOC, overall clinical status improved by 64% compared to those treated with SOC alone
- The SAVE-MORE trial, conducted by the Hellenic Institute for the Study of Sepsis, is the first large, pivotal randomised controlled trial to specifically evaluate a target patient population with COVID-19 at risk of progressing and demonstrating the benefit of earlier intervention with anakinra for the prevention of disease progression and reduced risk of mortality ....

United States , Kostenloser Wertpapierhandel , Maria Kruse , Evangelosj Giamarellos Bourboulis , Paula Treutiger , Guido Oelkers , European Shock Society , World Health Organization , Hellenic Institute For The Study Of Sepsis , Kapodistrian University Of Athens , European Sepsis Alliance , Hellenic Institute , Internal Medicine , Infectious Diseases , Kapodistrian University , European Sepsis , Progression Scale , Odds Ratio , Guided Anakinra Treatment , Severe Respiratory Failure , Professor Giamarellos Bourboulis , Familial Mediterranean , Systemic Juvenile Idiopathic Arthritis , Adult Onset Still , Intensive Care Units , North America ,