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Expansion of Clinical Development of RVU120 in Low-Risk Myelodysplastic Syndromes (LR-MDS)

Curis Announces Initiation of Investigator-Sponsored Phase 2 LUCAS Study of CA-4948 for the Treatment of Anemia in Patients with Very Low, Low, or Intermediate-Risk Myelodysplastic Syndromes

Published: Feb 02, 2021   LEXINGTON, Mass., Feb. 2, 2021 /PRNewswire/ Curis, Inc., (NASDAQ: CRIS), a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer, today announced the initiation of a Phase 2 investigator-sponsored trial (IST) evaluating CA-4948, a novel, small molecule IRAK4 kinase inhibitor, for the treatment of anemia in patients with very low, low, or intermediate-risk myelodysplastic syndromes (MDS). The study is being led by Uwe Platzbecker, M.D., Ph.D., Professor and Director of the Medical Clinic and Polyclinic for Hematology, Cell Therapy, and Hemostaseology at the University Hospital in Leipzig. Dr. Platzbecker is co-founder and chairman of both the European Myelodysplastic Syndromes Cooperative Group (EMSCO) and the German MDS Study Group (D-MDS). Furthermore, he acts as co-chairman of the European Hematology Association s Scientific Working Group on MDS.

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