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Whole genome sequencing may guide blood cancer treatment


Whole genome sequencing may guide blood cancer treatment
For certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), deciding whether patients need an aggressive treatment typically hinges on a set of lab tests to identify genetic changes.
Some of these tests rely on technology that was invented more than 60 years ago and has been used clinically for the past three decades.
Now, a new study from Washington University School of Medicine in St. Louis shows that whole genome sequencing is at least as accurate and often better than conventional genetic tests that help determine the treatment for a patient s blood cancer. Genome sequencing technology continuously is decreasing in cost and recently reached a level similar to that of conventional testing. In addition, results can be returned to patients in just a few days, making whole genome sequencing a potentially viable approach for determining the best treatment regimen for a parti ....

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Promising role for whole genome sequencing in guiding blood cancer treatment | The Source


Sequencing results returned in a few days; costs similar to conventional testing
A new study from Washington University School of Medicine shows that whole genome sequencing is at least as accurate and often better than conventional genetic tests that help determine the treatment for blood cancers, such as acute myeloid leukemia and myelodysplastic syndrome. (Photo: Getty Images)
March 10, 2021
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For certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), deciding whether patients need an aggressive treatment typically hinges on a set of lab tests to identify genetic changes. Some of these tests rely on technology that was invented more than 60 years ago and has been used clinically for the past three decades. ....

Ericj Duncavage , Mollyc Schroeder , Peter Campbell , Davidh Spencer , Eric Duncavage , Mcdonnell Genome Institute , Washington University , Siteman Cancer Center At Barnes , Wellcome Sanger Institute In Cambridge , Washington University School Of Medicine , Department Of Pathology Immunology , Siteman Cancer Center , Washington University School , New England Journal , Mcdonnell Genome , Barnes Jewish Hospital , Siteman Cancer , Wellcome Sanger Institute , பீட்டர் கேம்ப்பெல் , மக்டொநெல் மரபணு நிறுவனம் , வாஷிங்டன் பல்கலைக்கழகம் , வெல்கம் சாங்கர் நிறுவனம் இல் கேம்பிரிட்ஜ் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , துறை ஆஃப் நோயியல் நோயெதிர்ப்பு , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி , புதியது இங்கிலாந்து இதழ் ,

Promising role for whole genome sequencing in guiding blood cancer treatment – Washington University School of Medicine in St. Louis