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'Great news' as Pfizer Covid-19 vaccine proves 94% effective in real world


The research in Israel – two months into one of the world s fastest roll-outs, providing a rich source of data – showed two doses of the Pfizer shot cut symptomatic Covid-19 cases by 94 per cent across all age groups, and severe illnesses by nearly as much.
The study of about 1.2 million people also showed a single shot was 57 per cent effective in protecting against symptomatic infections after two weeks, according to the data published and peer-reviewed in the New England Journal of Medicine on Wednesday.
The results of the study for the Clalit Research Institute were close to those in clinical trials last year which found two doses were found to be 95 per cent effective. ....

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Israeli data confirms real-world efficiency rate of Covid-19 vaccine


The results of Israel s vaccination drive is continuing to inspire hope around the world. The first big real-world study of the Pfizer/BioNTech vaccine to be independently reviewed, based on data collected on the Israeli rollout, shows the shot is highly effective at preventing Covid-19, in a potentially landmark moment for countries desperate to end lockdowns and reopen economies.
 Up until now, most data on the efficacy of Covid-19 vaccines has come under controlled conditions in clinical trials, leaving an element of uncertainty over how results would translate into the real world with its unpredictable variables.
 
Ran Balicer, Director of Health Policy Planning at Clalit. Photo: Orel Cohen The research in Israel - two months into one of the world s fastest rollouts, providing a rich source of data - showed two doses of the Pfizer shot cut symptomatic Covid-19  cases by 94% across all age groups, and severe illnesses by nearly as much. ....

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Covid-19 vaccines performed well in clinical trials—but how are they doing in the real world?


Covid-19 vaccines did well in clinical trials. But how about in the real world?
Pfizer and
What early research reveals about the Covid-19 vaccines outside of clinical trials
For instance, in preliminary findings released Monday, one study looked at the entire 5.4 million population of Scotland between Dec. 8, 2020 and Feb. 15, when 1.14 million vaccine doses were administered. The researchers found that four weeks after a single initial dose, the risk of hospitalization declined by 85% among people who had received the Pfizer and BioNTech vaccine and by 94% among those who had received the AstraZeneca vaccine.
Similarly, preliminary data from
Public Health England found that, among people ages 80 and older, just one shot of the Pfizer and BioNTech vaccine reduced cases of Covid-19 by 57% and severe cases of Covid-19 by 75%, according to Chris Whitty, England s chief medical officer. According to the ....

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