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11-year-old Arizona boy able to get a life changing bone marrow transplant

TUCSON, Ariz. (KVOA) - An 11-year-old Arizona boy was able to get a life changing bone marrow transplant, about a year after being diagnosed with a rare blood disorder. ....

United States , William Anderson , Kimberlee Anderson , Epstein Bar , B Cell Lymphoma ,

Common viruses as triggers for Alzheimer's disease? The combined effect of cold sores and chickenpox viruses can lead to dementia

Common viruses as triggers for Alzheimer's disease? The combined effect of cold sores and chickenpox viruses can lead to dementia
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Dana Karens , Nadia Podebrigar , Tufts University , World Health Organization , Epstein Bar , Massachusetts Discoverinfection ,

Involvement of the Wnt pathway in BVDV cytopathogenic strain replication in primary bovine cells | Virology Journal

Bovine viral diarrhea virus 1 (BVDV-1) of the pestivirus genus is an economically crippling virus in the cattle industry; this positive RNA virus causes mucosal disease resulting in reproductive losses and other disease syndromes. The pathogenesis mechanism of the disease caused by BVDV infection is not well understood; for a better understanding of in vivo host BVDV-1 interactions, we conducted a transcriptomic study of infected cells at different times post-infection. We compared the permissiveness and cellular response of a BVDV-1 cytopathogenic strain on Madin-Darby Bovine Kidney cells (MDBK) and bovine lung primary cells, a model closer to in vivo infection. Then a RNAseq analysis was realized on the infected bovine lung primary cells, at 10 hpi and 30 hpi (hours post-infection), to identify transcriptomic signatures. RNAseq analysis on BVDV-1 infected bovine primary cells showed 2,759 and 5,376 differentially expressed genes at respectively 10 hpi and 30 hpi with an absolute Fold ....

Persistently Infected , Herpes Simplex , Epstein Bar , Human Immunodeficient , Rift Valley Fever ,