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ACMG releases new Points to Consider statement on the clinical utility of polygenic risk scores for embryo selection

Should we be using polygenic risk score assessment for embryo selection? Providing in-depth analysis, the Social, Ethical and Legal Issues Committee of the American College of Medical Genetics and Genomics (ACMG) has released a new Points to Consider statement to assist healthcare professionals and patients in understanding the safety and utility of preimplantation genetic testing for polygenic disorders (PGT-P) as a clinical service. ....

Susan Klugman , Theresaa Grebe , American College Of Medical Genetics , Medical Genetics , Legal Issues Committee , American College , Polygenic Risk Scores , Embryo Selection , Consider Statement , Cardiovascular Disease , N Vitro , Public Health ,

Understanding and addressing neurodevelopmental challenges in congenital heart disease

More than a decade of new knowledge about neurodevelopmental risk in people with congenital heart disease has changed the thinking about who is most at risk and the factors that impact neurological development, learning, emotions and behaviors, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation. ....

United States , Bradleys Marino , Council On Cardiovascular , American Heart Association , Nemours Children Health , Heart Health , Individuals With Congenital Heart Disease , Vice Chair , Nemours Children , Risk Category , Cardiac Neurodevelopmental Outcome Collaborative , Cleveland Clinic Children , Lifelong Congenital Heart Disease , Heart Association , Congenital Heart Disease , Heart Disease , Blood Vessels , Cardiac Surgery , Health Care ,